Does ciprofloxacin contain wheat or gluten as an excipient?

We cross-check each ciprofloxacin product label against four data sources: DailyMed (FDA Structured Product Labels), the European Medicines Agency centrally-authorised medicines database, the Plogsted curated gluten-free drug list, and the 2024 Mangione et al. pediatric pharmacy NDC analysis. Inactive ingredients are scanned against a 146-entry red-flag dictionary covering wheat, barley, rye, malt, source-ambiguous starches, and FDA gluten-free attestation phrases. At least one manufacturer has formally attested their formulation contains no gluten. Of 11 labels we checked, 1 are confirmed by the maker and 10 show nothing flagged. Confirm the brand or generic on your bottle matches one of the attesting manufacturers below.

Can different manufacturers' generic versions of ciprofloxacin have different gluten status?

Yes. Generics in the United States must use the same active ingredient as the brand, but they are not required to use the same inactive ingredients. Two generics of ciprofloxacin from different manufacturers can use entirely different starch sources, binders, and fillers. A pharmacy may also switch which manufacturer it dispenses between fills without notifying you. Each manufacturer-specific entry below corresponds to a separately-filed product label.

Last verified May 17, 2026 · 11 product labels screened

Is ciprofloxacin gluten-free?

Confirmed gluten-free by at least one manufacturer. At least one manufacturer has formally attested their formulation contains no gluten. Of 11 labels we checked, 1 are confirmed by the maker and 10 show nothing flagged. Confirm the brand or generic on your bottle matches one of the attesting manufacturers below.

Drug context

About ciprofloxacin

Ciprofloxacin is a fluoroquinolone antibiotic used for urinary, respiratory, and GI infections, sold under brand names including Cipro.

Why this matters

Different manufacturers, different ingredients

Generics of ciprofloxacin use the same active ingredient, but they aren't required to use the same inactive ingredients. Your pharmacy may switch which manufacturer they dispense between fills, sometimes without telling you. The list below shows each manufacturer's product label as a separate entry, because that's the granularity that actually matters when you're celiac.

The labels

The 11 we checked

01

(manufacturer not listed) manufacturer-attested gluten-free

Plogsted list · Cipro · label dated 2017-04-28

Listed gluten-free in Plogsted Alpha List (2017-04-28)
View source label →
02

Northwind Health Company, LLC nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN TABLET, FILM COATED [NORTHWIND HEALTH COMPANY, LLC] · label dated May 13, 2026

Inactive ingredients CROSPOVIDONE · HYPROMELLOSE, UNSPECIFIED · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL, UNSPECIFIED · SILICON DIOXIDE · STARCH, CORN · TITANIUM DIOXIDE · WATER
View source label →
03

Aurobindo Pharma Limited nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN (CIPROFLOXACIN HYDROCHLORIDE) TABLET, FILM COATED [AUROBINDO PHARMA LIMITED] · label dated May 12, 2026

Inactive ingredients ASCORBIC ACID · HYPROMELLOSE 2910 (5 MPA.S) · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE 101 · MICROCRYSTALLINE CELLULOSE 102 · POLYETHYLENE GLYCOL 400 · POVIDONE K30 · SILICON DIOXIDE · SODIUM STARCH GLYCOLATE TYPE A POTATO · TITANIUM DIOXIDE
View source label →
04

Advanced Rx Pharmacy of Tennessee, LLC nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN HCL TABLET, FILM COATED [ADVANCED RX PHARMACY OF TENNESSEE, LLC] · label dated May 11, 2026
View source label →
05

Redpharm Drug nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN HYDROCHLORIDE SOLUTION/ DROPS [REDPHARM DRUG] · label dated May 06, 2026

Inactive ingredients ACETIC ACID · BENZALKONIUM CHLORIDE · EDETATE DISODIUM · HYDROCHLORIC ACID · MANNITOL · SODIUM ACETATE · SODIUM HYDROXIDE · WATER
View source label →
06

Asclemed USA, Inc. nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN (CIPROFLOXACIN HYDROCHLORIDE) TABLET, FILM COATED [ASCLEMED USA, INC.] · label dated Apr 30, 2026

Inactive ingredients HYPROMELLOSE 2910 (5 MPA.S) · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE · POLYETHYLENE GLYCOL 400 · POVIDONE K30 · SILICON DIOXIDE · SODIUM STARCH GLYCOLATE TYPE A POTATO · TITANIUM DIOXIDE
View source label →
07

NCS HealthCare of KY, LLC dba Vangard Labs nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN (CIPROFLOXACIN HYDROCHLORIDE) TABLET, FILM COATED [NCS HEALTHCARE OF KY, … · label dated Apr 27, 2026

Inactive ingredients ASCORBIC ACID · HYPROMELLOSE 2910 (5 MPA.S) · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE 101 · MICROCRYSTALLINE CELLULOSE 102 · POLYETHYLENE GLYCOL 400 · POVIDONE K30 · SILICON DIOXIDE · SODIUM STARCH GLYCOLATE TYPE A POTATO · TITANIUM DIOXIDE
View source label →
08

Sportpharm LLC nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN (CIPROFOLXACIN) TABLET [SPORTPHARM LLC] · label dated Apr 27, 2026

Inactive ingredients HYPROMELLOSE, UNSPECIFIED · MAGNESIUM STEARATE · MICROCRYSTALLINE CELLULOSE · MODIFIED CORN STARCH (1-OCTENYL SUCCINIC ANHYDRIDE) · POLYETHYLENE GLYCOL, UNSPECIFIED · SILICON DIOXIDE · SODIUM STARCH GLYCOLATE TYPE A CORN · STARCH, CORN · TITANIUM DIOXIDE
View source label →
09

Sentiss Pharmaceuticals LLC nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN AND DEXAMETHASONE SUSPENSION/ DROPS [SENTISS PHARMACEUTICALS LLC] · label dated Apr 17, 2026

Inactive ingredients ACETIC ACID · BENZALKONIUM CHLORIDE · BORIC ACID · EDETATE DISODIUM · HYDROCHLORIC ACID · HYDROXYETHYL CELLULOSE, UNSPECIFIED · SODIUM ACETATE · SODIUM CHLORIDE · SODIUM HYDROXIDE · TYLOXAPOL · WATER
View source label →
10

Sun Pharmaceutical Industries, Inc. nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN AND DEXAMETHASONE SUSPENSION/ DROPS [SUN PHARMACEUTICAL INDUSTRIES, INC.] · label dated Apr 03, 2026

Inactive ingredients ACETIC ACID · BENZALKONIUM CHLORIDE · BORIC ACID · EDETATE DISODIUM · HYDROCHLORIC ACID · HYDROXYETHYL CELLULOSE (2000 MPA.S AT 1%) · SODIUM ACETATE · SODIUM CHLORIDE · SODIUM HYDROXIDE · TYLOXAPOL · Water
View source label →
11

Upsher-Smith Laboratories, LLC nothing flagged on the label

US label (DailyMed) · CIPROFLOXACIN AND DEXAMETHASONE (CIPROFLOXACIN HYDROCHLORIDE AND DEXAMETHASONE) SUSPENS… · label dated Mar 25, 2026

Inactive ingredients ACETIC ACID · BENZALKONIUM CHLORIDE · BORIC ACID · EDETATE DISODIUM · HYDROCHLORIC ACID · HYDROXYETHYL CELLULOSE (1500 MPA.S AT 1%) · SODIUM ACETATE · SODIUM CHLORIDE · SODIUM HYDROXIDE · TYLOXAPOL · WATER
View source label →

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Background

What “gluten in a medication” actually means

Gluten enters drugs through their excipients — the inactive ingredients used to bind, coat, fill, or stabilize the dose. The main concern is wheat starch as a filler. Source-ambiguous starches (plain “starch”, pregelatinized starch, sodium starch glycolate, modified starch) get flagged for verification because their botanical origin isn't always disclosed on the label.

The 2024 Mangione et al. pediatric NDC analysis (689 NDCs across the top 100 pediatric medications) found 1.5% contained gluten outright; another 25.7% couldn't be confirmed either way. Liquid and oral-suspension formulations carry disproportionate risk because wheat starch is a common thickener. Full methodology →

Keep checking

Other drugs people look up

Important. This page is informational. Drug labels can change without notice; a manufacturer attestation is point-in-time, not a warranty. If you have celiac disease and your pharmacy switches manufacturers, re-screen the new label before taking the dispensed product. For a definitive answer, call the manufacturer's medical-information line with the NDC code from your prescription bottle.